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Oct 29

BPKD: Boundary Privileged Knowledge Distillation For Semantic Segmentation

Current knowledge distillation approaches in semantic segmentation tend to adopt a holistic approach that treats all spatial locations equally. However, for dense prediction, students' predictions on edge regions are highly uncertain due to contextual information leakage, requiring higher spatial sensitivity knowledge than the body regions. To address this challenge, this paper proposes a novel approach called boundary-privileged knowledge distillation (BPKD). BPKD distills the knowledge of the teacher model's body and edges separately to the compact student model. Specifically, we employ two distinct loss functions: (i) edge loss, which aims to distinguish between ambiguous classes at the pixel level in edge regions; (ii) body loss, which utilizes shape constraints and selectively attends to the inner-semantic regions. Our experiments demonstrate that the proposed BPKD method provides extensive refinements and aggregation for edge and body regions. Additionally, the method achieves state-of-the-art distillation performance for semantic segmentation on three popular benchmark datasets, highlighting its effectiveness and generalization ability. BPKD shows consistent improvements across a diverse array of lightweight segmentation structures, including both CNNs and transformers, underscoring its architecture-agnostic adaptability. The code is available at https://github.com/AkideLiu/BPKD.

  • 6 authors
·
Jun 13, 2023

View-Consistent Hierarchical 3D Segmentation Using Ultrametric Feature Fields

Large-scale vision foundation models such as Segment Anything (SAM) demonstrate impressive performance in zero-shot image segmentation at multiple levels of granularity. However, these zero-shot predictions are rarely 3D-consistent. As the camera viewpoint changes in a scene, so do the segmentation predictions, as well as the characterizations of "coarse" or "fine" granularity. In this work, we address the challenging task of lifting multi-granular and view-inconsistent image segmentations into a hierarchical and 3D-consistent representation. We learn a novel feature field within a Neural Radiance Field (NeRF) representing a 3D scene, whose segmentation structure can be revealed at different scales by simply using different thresholds on feature distance. Our key idea is to learn an ultrametric feature space, which unlike a Euclidean space, exhibits transitivity in distance-based grouping, naturally leading to a hierarchical clustering. Put together, our method takes view-inconsistent multi-granularity 2D segmentations as input and produces a hierarchy of 3D-consistent segmentations as output. We evaluate our method and several baselines on synthetic datasets with multi-view images and multi-granular segmentation, showcasing improved accuracy and viewpoint-consistency. We additionally provide qualitative examples of our model's 3D hierarchical segmentations in real world scenes. The code and dataset are available at https://github.com/hardyho/ultrametric_feature_fields

  • 4 authors
·
May 30, 2024

You Only Look at Once for Real-time and Generic Multi-Task

High precision, lightweight, and real-time responsiveness are three essential requirements for implementing autonomous driving. In this study, we incorporate A-YOLOM, an adaptive, real-time, and lightweight multi-task model designed to concurrently address object detection, drivable area segmentation, and lane line segmentation tasks. Specifically, we develop an end-to-end multi-task model with a unified and streamlined segmentation structure. We introduce a learnable parameter that adaptively concatenates features between necks and backbone in segmentation tasks, using the same loss function for all segmentation tasks. This eliminates the need for customizations and enhances the model's generalization capabilities. We also introduce a segmentation head composed only of a series of convolutional layers, which reduces the number of parameters and inference time. We achieve competitive results on the BDD100k dataset, particularly in visualization outcomes. The performance results show a mAP50 of 81.1% for object detection, a mIoU of 91.0% for drivable area segmentation, and an IoU of 28.8% for lane line segmentation. Additionally, we introduce real-world scenarios to evaluate our model's performance in a real scene, which significantly outperforms competitors. This demonstrates that our model not only exhibits competitive performance but is also more flexible and faster than existing multi-task models. The source codes and pre-trained models are released at https://github.com/JiayuanWang-JW/YOLOv8-multi-task

  • 3 authors
·
Oct 2, 2023

Robust Multispectral Semantic Segmentation under Missing or Full Modalities via Structured Latent Projection

Multimodal remote sensing data provide complementary information for semantic segmentation, but in real-world deployments, some modalities may be unavailable due to sensor failures, acquisition issues, or challenging atmospheric conditions. Existing multimodal segmentation models typically address missing modalities by learning a shared representation across inputs. However, this approach can introduce a trade-off by compromising modality-specific complementary information and reducing performance when all modalities are available. In this paper, we tackle this limitation with CBC-SLP, a multimodal semantic segmentation model designed to preserve both modality-invariant and modality-specific information. Inspired by the theoretical results on modality alignment, which state that perfectly aligned multimodal representations can lead to sub-optimal performance in downstream prediction tasks, we propose a novel structured latent projection approach as an architectural inductive bias. Rather than enforcing this strategy through a loss term, we incorporate it directly into the architecture. In particular, to use the complementary information effectively while maintaining robustness under random modality dropout, we structure the latent representations into shared and modality-specific components and adaptively transfer them to the decoder according to the random modality availability mask. Extensive experiments on three multimodal remote sensing image sets demonstrate that CBC-SLP consistently outperforms state-of-the-art multimodal models across full and missing modality scenarios. Besides, we empirically demonstrate that the proposed strategy can recover the complementary information that may not be preserved in a shared representation. The code is available at https://github.com/iremulku/Multispectral-Semantic-Segmentation-via-Structured-Latent-Projection-CBC-SLP-.

  • 3 authors
·
Apr 16

SpinalSAM-R1: A Vision-Language Multimodal Interactive System for Spine CT Segmentation

The anatomical structure segmentation of the spine and adjacent structures from computed tomography (CT) images is a key step for spinal disease diagnosis and treatment. However, the segmentation of CT images is impeded by low contrast and complex vertebral boundaries. Although advanced models such as the Segment Anything Model (SAM) have shown promise in various segmentation tasks, their performance in spinal CT imaging is limited by high annotation requirements and poor domain adaptability. To address these limitations, we propose SpinalSAM-R1, a multimodal vision-language interactive system that integrates a fine-tuned SAM with DeepSeek-R1, for spine CT image segmentation. Specifically, our SpinalSAM-R1 introduces an anatomy-guided attention mechanism to improve spine segmentation performance, and a semantics-driven interaction protocol powered by DeepSeek-R1, enabling natural language-guided refinement. The SpinalSAM-R1 is fine-tuned using Low-Rank Adaptation (LoRA) for efficient adaptation. We validate our SpinalSAM-R1 on the spine anatomical structure with CT images. Experimental results suggest that our method achieves superior segmentation performance. Meanwhile, we develop a PyQt5-based interactive software, which supports point, box, and text-based prompts. The system supports 11 clinical operations with 94.3\% parsing accuracy and sub-800 ms response times. The software is released on https://github.com/6jm233333/spinalsam-r1.

  • 6 authors
·
Oct 30, 2025

GraphEcho: Graph-Driven Unsupervised Domain Adaptation for Echocardiogram Video Segmentation

Echocardiogram video segmentation plays an important role in cardiac disease diagnosis. This paper studies the unsupervised domain adaption (UDA) for echocardiogram video segmentation, where the goal is to generalize the model trained on the source domain to other unlabelled target domains. Existing UDA segmentation methods are not suitable for this task because they do not model local information and the cyclical consistency of heartbeat. In this paper, we introduce a newly collected CardiacUDA dataset and a novel GraphEcho method for cardiac structure segmentation. Our GraphEcho comprises two innovative modules, the Spatial-wise Cross-domain Graph Matching (SCGM) and the Temporal Cycle Consistency (TCC) module, which utilize prior knowledge of echocardiogram videos, i.e., consistent cardiac structure across patients and centers and the heartbeat cyclical consistency, respectively. These two modules can better align global and local features from source and target domains, improving UDA segmentation results. Experimental results showed that our GraphEcho outperforms existing state-of-the-art UDA segmentation methods. Our collected dataset and code will be publicly released upon acceptance. This work will lay a new and solid cornerstone for cardiac structure segmentation from echocardiogram videos. Code and dataset are available at: https://github.com/xmed-lab/GraphEcho

  • 5 authors
·
Sep 20, 2023

UU-Mamba: Uncertainty-aware U-Mamba for Cardiovascular Segmentation

Building on the success of deep learning models in cardiovascular structure segmentation, increasing attention has been focused on improving generalization and robustness, particularly in small, annotated datasets. Despite recent advancements, current approaches often face challenges such as overfitting and accuracy limitations, largely due to their reliance on large datasets and narrow optimization techniques. This paper introduces the UU-Mamba model, an extension of the U-Mamba architecture, designed to address these challenges in both cardiac and vascular segmentation. By incorporating Sharpness-Aware Minimization (SAM), the model enhances generalization by targeting flatter minima in the loss landscape. Additionally, we propose an uncertainty-aware loss function that combines region-based, distribution-based, and pixel-based components to improve segmentation accuracy by capturing both local and global features. While the UU-Mamba model has already demonstrated great performance, further testing is required to fully assess its generalization and robustness. We expand our evaluation by conducting new trials on the ImageCAS (coronary artery) and Aorta (aortic branches and zones) datasets, which present more complex segmentation challenges than the ACDC dataset (left and right ventricles) used in our previous work, showcasing the model's adaptability and resilience. We confirm UU-Mamba's superior performance over leading models such as TransUNet, Swin-Unet, nnUNet, and nnFormer. Moreover, we provide a more comprehensive evaluation of the model's robustness and segmentation accuracy, as demonstrated by extensive experiments.

  • 8 authors
·
Sep 21, 2024

Diffusion Model as a Generalist Segmentation Learner

Diffusion models are primarily trained for image synthesis, yet their denoising trajectories encode rich, spatially aligned visual priors. In this paper, we demonstrate that these priors can be utilized for text-conditioned semantic and open-vocabulary segmentation, and this approach can be generalized to various downstream tasks to make a general-purpose diffusion segmentation framework. Concretely, we introduce DiGSeg (Diffusion Models as a Generalist Segmentation Learner), which repurposes a pretrained diffusion model into a unified segmentation framework. Our approach encodes the input image and ground-truth mask into the latent space and concatenates them as conditioning signals for the diffusion U-Net. A parallel CLIP-aligned text pathway injects language features across multiple scales, enabling the model to align textual queries with evolving visual representations. This design transforms an off-the-shelf diffusion backbone into a universal interface that produces structured segmentation masks conditioned on both appearance and arbitrary text prompts. Extensive experiments demonstrate state-of-the-art performance on standard semantic segmentation benchmarks, as well as strong open-vocabulary generalization and cross-domain transfer to medical, remote sensing, and agricultural scenarios-without domain-specific architectural customization. These results indicate that modern diffusion backbones can serve as generalist segmentation learners rather than pure generators, narrowing the gap between visual generation and visual understanding.

  • 11 authors
·
Apr 26 2

PanoOcc: Unified Occupancy Representation for Camera-based 3D Panoptic Segmentation

Comprehensive modeling of the surrounding 3D world is key to the success of autonomous driving. However, existing perception tasks like object detection, road structure segmentation, depth & elevation estimation, and open-set object localization each only focus on a small facet of the holistic 3D scene understanding task. This divide-and-conquer strategy simplifies the algorithm development procedure at the cost of losing an end-to-end unified solution to the problem. In this work, we address this limitation by studying camera-based 3D panoptic segmentation, aiming to achieve a unified occupancy representation for camera-only 3D scene understanding. To achieve this, we introduce a novel method called PanoOcc, which utilizes voxel queries to aggregate spatiotemporal information from multi-frame and multi-view images in a coarse-to-fine scheme, integrating feature learning and scene representation into a unified occupancy representation. We have conducted extensive ablation studies to verify the effectiveness and efficiency of the proposed method. Our approach achieves new state-of-the-art results for camera-based semantic segmentation and panoptic segmentation on the nuScenes dataset. Furthermore, our method can be easily extended to dense occupancy prediction and has shown promising performance on the Occ3D benchmark. The code will be released at https://github.com/Robertwyq/PanoOcc.

  • 5 authors
·
Jun 16, 2023

Joint Self-Supervised Image-Volume Representation Learning with Intra-Inter Contrastive Clustering

Collecting large-scale medical datasets with fully annotated samples for training of deep networks is prohibitively expensive, especially for 3D volume data. Recent breakthroughs in self-supervised learning (SSL) offer the ability to overcome the lack of labeled training samples by learning feature representations from unlabeled data. However, most current SSL techniques in the medical field have been designed for either 2D images or 3D volumes. In practice, this restricts the capability to fully leverage unlabeled data from numerous sources, which may include both 2D and 3D data. Additionally, the use of these pre-trained networks is constrained to downstream tasks with compatible data dimensions. In this paper, we propose a novel framework for unsupervised joint learning on 2D and 3D data modalities. Given a set of 2D images or 2D slices extracted from 3D volumes, we construct an SSL task based on a 2D contrastive clustering problem for distinct classes. The 3D volumes are exploited by computing vectored embedding at each slice and then assembling a holistic feature through deformable self-attention mechanisms in Transformer, allowing incorporating long-range dependencies between slices inside 3D volumes. These holistic features are further utilized to define a novel 3D clustering agreement-based SSL task and masking embedding prediction inspired by pre-trained language models. Experiments on downstream tasks, such as 3D brain segmentation, lung nodule detection, 3D heart structures segmentation, and abnormal chest X-ray detection, demonstrate the effectiveness of our joint 2D and 3D SSL approach. We improve plain 2D Deep-ClusterV2 and SwAV by a significant margin and also surpass various modern 2D and 3D SSL approaches.

  • 10 authors
·
Dec 4, 2022

RadGenome-Anatomy: A Large-Scale Anatomy-Labeled Chest Radiograph Dataset via Physically Grounded Volumetric Projection

Anatomical structure labels for chest radiographs are essential for medical image segmentation and a broad range of downstream diagnostic tasks. However, annotating anatomy directly on 2D chest radiographs is labor-intensive and intrinsically ambiguous, as 3D anatomical structures are projected onto a single 2D plane where boundaries may overlap, be occluded, or appear only partially visible. Consequently, existing anatomy-labeled chest radiograph datasets remain limited in scale, anatomy coverage, and label reliability. To address these limitations, we introduce RadGenome-Anatomy, the largest anatomy-labeled chest radiograph dataset, containing over 10 million segmentation masks across 210 anatomical structures in 25,692 studies. It is constructed by projecting large-scale 3D anatomical masks from CT volumes into 2D radiographic space through canonical radiographic geometry. This shifts annotation from directly tracing uncertain 2D boundaries to defining anatomy in volumetric space, where structures that overlap or become partially invisible in radiographs remain spatially separable. As a result, each 2D mask represents the physically grounded projected footprint of a volumetrically defined structure. The scale and broad anatomical coverage of RadGenome-Anatomy, including structures that are overlapping, partially visible, or difficult to delineate directly, enable research on geometric measurements as explicit evidence for chest radiograph interpretation. We demonstrate this by training XAnatomy to predict structure-specific masks and derive clinically relevant measurements, achieving diagnostic accuracies of 96.4%, 95.6%, and 89.2% for cardiomegaly, kyphosis, and scoliosis, respectively.

  • 5 authors
·
May 16

FetalCLIP: A Visual-Language Foundation Model for Fetal Ultrasound Image Analysis

Foundation models are becoming increasingly effective in the medical domain, offering pre-trained models on large datasets that can be readily adapted for downstream tasks. Despite progress, fetal ultrasound images remain a challenging domain for foundation models due to their inherent complexity, often requiring substantial additional training and facing limitations due to the scarcity of paired multimodal data. To overcome these challenges, here we introduce FetalCLIP, a vision-language foundation model capable of generating universal representation of fetal ultrasound images. FetalCLIP was pre-trained using a multimodal learning approach on a diverse dataset of 210,035 fetal ultrasound images paired with text. This represents the largest paired dataset of its kind used for foundation model development to date. This unique training approach allows FetalCLIP to effectively learn the intricate anatomical features present in fetal ultrasound images, resulting in robust representations that can be used for a variety of downstream applications. In extensive benchmarking across a range of key fetal ultrasound applications, including classification, gestational age estimation, congenital heart defect (CHD) detection, and fetal structure segmentation, FetalCLIP outperformed all baselines while demonstrating remarkable generalizability and strong performance even with limited labeled data. We plan to release the FetalCLIP model publicly for the benefit of the broader scientific community.

  • 11 authors
·
Feb 20, 2025

TotalSegmentator MRI: Robust Sequence-independent Segmentation of Multiple Anatomic Structures in MRI

Since the introduction of TotalSegmentator CT, there is demand for a similar robust automated MRI segmentation tool that can be applied across all MRI sequences and anatomic structures. In this retrospective study, a nnU-Net model (TotalSegmentator) was trained on MRI and CT examinations to segment 80 anatomic structures relevant for use cases such as organ volumetry, disease characterization, surgical planning and opportunistic screening. Examinations were randomly sampled from routine clinical studies to represent real-world examples. Dice scores were calculated between the predicted segmentations and expert radiologist reference standard segmentations to evaluate model performance on an internal test set, two external test sets and against two publicly available models, and TotalSegmentator CT. The model was applied to an internal dataset containing abdominal MRIs to investigate age-dependent volume changes. A total of 1143 examinations (616 MRIs, 527 CTs) (median age 61 years, IQR 50-72) were split into training (n=1088, CT and MRI) and an internal test set (n=55; only MRI), two external test sets (AMOS, n=20; CHAOS, n=20; only MRI), and an internal aging-study dataset of 8672 abdominal MRIs (median age 59 years, IQR 45-70) were included. The model showed a Dice Score of 0.839 on the internal test set and outperformed two other models (Dice Score, 0.862 versus 0.759; and 0.838 versus 0.560; p<.001 for both). The proposed open-source, easy-to-use model allows for automatic, robust segmentation of 80 structures, extending the capabilities of TotalSegmentator to MRIs of any sequence. The ready-to-use online tool is available at https://totalsegmentator.com, the model at https://github.com/wasserth/TotalSegmentator, and the dataset at https://zenodo.org/records/14710732.

  • 19 authors
·
May 29, 2024

MedCLIP-SAMv2: Towards Universal Text-Driven Medical Image Segmentation

Segmentation of anatomical structures and pathological regions in medical images is essential for modern clinical diagnosis, disease research, and treatment planning. While significant advancements have been made in deep learning-based segmentation techniques, many of these methods still suffer from limitations in data efficiency, generalizability, and interactivity. As a result, developing precise segmentation methods that require fewer labeled datasets remains a critical challenge in medical image analysis. Recently, the introduction of foundation models like CLIP and Segment-Anything-Model (SAM), with robust cross-domain representations, has paved the way for interactive and universal image segmentation. However, further exploration of these models for data-efficient segmentation in medical imaging is still needed and highly relevant. In this paper, we introduce MedCLIP-SAMv2, a novel framework that integrates the CLIP and SAM models to perform segmentation on clinical scans using text prompts, in both zero-shot and weakly supervised settings. Our approach includes fine-tuning the BiomedCLIP model with a new Decoupled Hard Negative Noise Contrastive Estimation (DHN-NCE) loss, and leveraging the Multi-modal Information Bottleneck (M2IB) to create visual prompts for generating segmentation masks from SAM in the zero-shot setting. We also investigate using zero-shot segmentation labels within a weakly supervised paradigm to enhance segmentation quality further. Extensive testing across four diverse segmentation tasks and medical imaging modalities (breast tumor ultrasound, brain tumor MRI, lung X-ray, and lung CT) demonstrates the high accuracy of our proposed framework. Our code is available at https://github.com/HealthX-Lab/MedCLIP-SAMv2.

  • 4 authors
·
Sep 28, 2024

MedCLIP-SAM: Bridging Text and Image Towards Universal Medical Image Segmentation

Medical image segmentation of anatomical structures and pathology is crucial in modern clinical diagnosis, disease study, and treatment planning. To date, great progress has been made in deep learning-based segmentation techniques, but most methods still lack data efficiency, generalizability, and interactability. Consequently, the development of new, precise segmentation methods that demand fewer labeled datasets is of utmost importance in medical image analysis. Recently, the emergence of foundation models, such as CLIP and Segment-Anything-Model (SAM), with comprehensive cross-domain representation opened the door for interactive and universal image segmentation. However, exploration of these models for data-efficient medical image segmentation is still limited, but is highly necessary. In this paper, we propose a novel framework, called MedCLIP-SAM that combines CLIP and SAM models to generate segmentation of clinical scans using text prompts in both zero-shot and weakly supervised settings. To achieve this, we employed a new Decoupled Hard Negative Noise Contrastive Estimation (DHN-NCE) loss to fine-tune the BiomedCLIP model and the recent gScoreCAM to generate prompts to obtain segmentation masks from SAM in a zero-shot setting. Additionally, we explored the use of zero-shot segmentation labels in a weakly supervised paradigm to improve the segmentation quality further. By extensively testing three diverse segmentation tasks and medical image modalities (breast tumor ultrasound, brain tumor MRI, and lung X-ray), our proposed framework has demonstrated excellent accuracy. Code is available at https://github.com/HealthX-Lab/MedCLIP-SAM.

  • 4 authors
·
Mar 29, 2024

SAS: Segment Anything Small for Ultrasound -- A Non-Generative Data Augmentation Technique for Robust Deep Learning in Ultrasound Imaging

Accurate segmentation of anatomical structures in ultrasound (US) images, particularly small ones, is challenging due to noise and variability in imaging conditions (e.g., probe position, patient anatomy, tissue characteristics and pathology). To address this, we introduce Segment Anything Small (SAS), a simple yet effective scale- and texture-aware data augmentation technique designed to enhance the performance of deep learning models for segmenting small anatomical structures in ultrasound images. SAS employs a dual transformation strategy: (1) simulating diverse organ scales by resizing and embedding organ thumbnails into a black background, and (2) injecting noise into regions of interest to simulate varying tissue textures. These transformations generate realistic and diverse training data without introducing hallucinations or artifacts, improving the model's robustness to noise and variability. We fine-tuned a promptable foundation model on a controlled organ-specific medical imaging dataset and evaluated its performance on one internal and five external datasets. Experimental results demonstrate significant improvements in segmentation performance, with Dice score gains of up to 0.35 and an average improvement of 0.16 [95% CI 0.132,0.188]. Additionally, our iterative point prompts provide precise control and adaptive refinement, achieving performance comparable to bounding box prompts with just two points. SAS enhances model robustness and generalizability across diverse anatomical structures and imaging conditions, particularly for small structures, without compromising the accuracy of larger ones. By offering a computationally efficient solution that eliminates the need for extensive human labeling efforts, SAS emerges as a powerful tool for advancing medical image analysis, particularly in resource-constrained settings.

  • 5 authors
·
Mar 7, 2025

ForestSim: A Synthetic Benchmark for Intelligent Vehicle Perception in Unstructured Forest Environments

Robust scene understanding is essential for intelligent vehicles operating in natural, unstructured environments. While semantic segmentation datasets for structured urban driving are abundant, the datasets for extremely unstructured wild environments remain scarce due to the difficulty and cost of generating pixel-accurate annotations. These limitations hinder the development of perception systems needed for intelligent ground vehicles tasked with forestry automation, agricultural robotics, disaster response, and all-terrain mobility. To address this gap, we present ForestSim, a high-fidelity synthetic dataset designed for training and evaluating semantic segmentation models for intelligent vehicles in forested off-road and no-road environments. ForestSim contains 2094 photorealistic images across 25 diverse environments, covering multiple seasons, terrain types, and foliage densities. Using Unreal Engine environments integrated with Microsoft AirSim, we generate consistent, pixel-accurate labels across 20 classes relevant to autonomous navigation. We benchmark ForestSim using state-of-the-art architectures and report strong performance despite the inherent challenges of unstructured scenes. ForestSim provides a scalable and accessible foundation for perception research supporting the next generation of intelligent off-road vehicles. The dataset and code are publicly available: Dataset: https://vailforestsim.github.io Code: https://github.com/pragatwagle/ForestSim

  • 3 authors
·
Mar 29

Learning Generalizable 3D Medical Image Representations from Mask-Guided Self-Supervision

Foundation models have transformed vision and language by learning general-purpose representations from large-scale unlabeled data, yet 3D medical imaging lacks analogous approaches. Existing self-supervised methods rely on low-level reconstruction or contrastive objectives that fail to capture the anatomical semantics critical for medical image analysis, limiting transfer to downstream tasks. We present MASS (MAsk-guided Self-Supervised learning), which treats in-context segmentation as the pretext task for learning general-purpose medical imaging representations. MASS's key insight is that automatically generated class-agnostic masks provide sufficient structural supervision for learning semantically rich representations. By training on thousands of diverse mask proposals spanning anatomical structures and pathological findings, MASS learns what semantically defines medical structures: the holistic combination of appearance, shape, spatial context, and anatomical relationships. We demonstrate effectiveness across data regimes: from small-scale pretraining on individual datasets (20-200 scans) to large-scale multi-modal pretraining on 5K CT, MRI, and PET volumes, all without annotations. MASS demonstrates: (i) few-shot segmentation on novel structures, (ii) matching full supervision with only 20-40\% labeled data while outperforming self-supervised baselines by over 20 in Dice score in low-data regimes, and (iii) frozen-encoder classification on unseen pathologies that matches full supervised training with thousands of samples. Mask-guided self-supervised pretraining captures broadly generalizable knowledge, opening a path toward 3D medical imaging foundation models without expert annotations. Code is available: https://github.com/Stanford-AIMI/MASS.

  • 8 authors
·
Mar 13

Detailed Annotations of Chest X-Rays via CT Projection for Report Understanding

In clinical radiology reports, doctors capture important information about the patient's health status. They convey their observations from raw medical imaging data about the inner structures of a patient. As such, formulating reports requires medical experts to possess wide-ranging knowledge about anatomical regions with their normal, healthy appearance as well as the ability to recognize abnormalities. This explicit grasp on both the patient's anatomy and their appearance is missing in current medical image-processing systems as annotations are especially difficult to gather. This renders the models to be narrow experts e.g. for identifying specific diseases. In this work, we recover this missing link by adding human anatomy into the mix and enable the association of content in medical reports to their occurrence in associated imagery (medical phrase grounding). To exploit anatomical structures in this scenario, we present a sophisticated automatic pipeline to gather and integrate human bodily structures from computed tomography datasets, which we incorporate in our PAXRay: A Projected dataset for the segmentation of Anatomical structures in X-Ray data. Our evaluation shows that methods that take advantage of anatomical information benefit heavily in visually grounding radiologists' findings, as our anatomical segmentations allow for up to absolute 50% better grounding results on the OpenI dataset as compared to commonly used region proposals. The PAXRay dataset is available at https://constantinseibold.github.io/paxray/.

  • 10 authors
·
Oct 7, 2022

BAAI Cardiac Agent: An intelligent multimodal agent for automated reasoning and diagnosis of cardiovascular diseases from cardiac magnetic resonance imaging

Cardiac magnetic resonance (CMR) is a cornerstone for diagnosing cardiovascular disease. However, it remains underutilized due to complex, time-consuming interpretation across multi-sequences, phases, quantitative measures that heavily reliant on specialized expertise. Here, we present BAAI Cardiac Agent, a multimodal intelligent system designed for end-to-end CMR interpretation. The agent integrates specialized cardiac expert models to perform automated segmentation of cardiac structures, functional quantification, tissue characterization and disease diagnosis, and generates structured clinical reports within a unified workflow. Evaluated on CMR datasets from two hospitals (2413 patients) spanning 7-types of major cardiovascular diseases, the agent achieved an area under the receiver-operating-characteristic curve exceeding 0.93 internally and 0.81 externally. In the task of estimating left ventricular function indices, the results generated by this system for core parameters such as ejection fraction, stroke volume, and left ventricular mass are highly consistent with clinical reports, with Pearson correlation coefficients all exceeding 0.90. The agent outperformed state-of-the-art models in segmentation and diagnostic tasks, and generated clinical reports showing high concordance with expert radiologists (six readers across three experience levels). By dynamically orchestrating expert models for coordinated multimodal analysis, this agent framework enables accurate, efficient CMR interpretation and highlights its potentials for complex clinical imaging workflows. Code is available at https://github.com/plantain-herb/Cardiac-Agent.

  • 21 authors
·
Apr 4

AI Agent for Reverse-Engineering Legacy Finite-Difference Code and Translating to Devito

To facilitate the transformation of legacy finite difference implementations into the Devito environment, this study develops an integrated AI agent framework. Retrieval-Augmented Generation (RAG) and open-source Large Language Models are combined through multi-stage iterative workflows in the system's hybrid LangGraph architecture. The agent constructs an extensive Devito knowledge graph through document parsing, structure-aware segmentation, extraction of entity relationships, and Leiden-based community detection. GraphRAG optimisation enhances query performance across semantic communities that include seismic wave simulation, computational fluid dynamics, and performance tuning libraries. A reverse engineering component derives three-level query strategies for RAG retrieval through static analysis of Fortran source code. To deliver precise contextual information for language model guidance, the multi-stage retrieval pipeline performs parallel searching, concept expansion, community-scale retrieval, and semantic similarity analysis. Code synthesis is governed by Pydantic-based constraints to guarantee structured outputs and reliability. A comprehensive validation framework integrates conventional static analysis with the G-Eval approach, covering execution correctness, structural soundness, mathematical consistency, and API compliance. The overall agent workflow is implemented on the LangGraph framework and adopts concurrent processing to support quality-based iterative refinement and state-aware dynamic routing. The principal contribution lies in the incorporation of feedback mechanisms motivated by reinforcement learning, enabling a transition from static code translation toward dynamic and adaptive analytical behavior.

  • 2 authors
·
Jan 25

RAM-H1200: A Unified Evaluation and Dataset on Hand Radiographs for Rheumatoid Arthritis

Rheumatoid arthritis (RA) assessment from hand radiographs requires multi-level analysis and modeling of anatomical structures and fine-grained local pathological changes. However, existing public resources do not support such unified multi-level analysis, often lacking full-hand coverage, fine-grained annotations, and consistent integration with clinical scoring systems. In particular, annotations that enable quantitative analysis of bone erosion (BE) remain scarce. RAM-H1200 contains 1,200 hand radiographs collected from six medical centers, with multi-level annotations including (i) whole-hand bone structure instance segmentation, (ii) pixel-level BE masks, (iii) SvdH-defined joint regions of interest, and (iv) joint-level SvdH scores for both BE and joint space narrowing (JSN). It is designed to evaluate whether models can jointly capture anatomical structure, localized erosive pathology, and clinically standardized RA severity from hand radiographs. The proposed BE masks enable, for the first time, quantitative BE analysis beyond coarse categorical grading by providing explicit spatial supervision for lesion extent and morphology. To our knowledge, RAM-H1200 is the first public large-scale benchmark that jointly supports whole-hand bone structure instance segmentation, pixel-level BE delineation, and clinically grounded joint-level SvdH scoring for both BE and JSN. Results across benchmark tasks show that anatomical modeling is substantially more mature than quantitative BE analysis: whole-hand bone segmentation achieves strong performance, whereas BE segmentation remains a major open challenge. By unifying anatomical structure modeling, quantitative lesion analysis, and clinically grounded SvdH scoring, RAM-H1200 provides a single benchmark for comprehensive RA analysis on hand radiographs.

  • 12 authors
·
May 6

Thinking with Anchors: Grounded and Efficient Document Reasoning

Existing document understanding benchmarks have largely focused on locating page elements, yet real-world document intelligence requires models to reason jointly about region semantics, spatial relations, and visual structure. We present ADOPD 2026, a reasoning-oriented extension of ADOPD that turns page decomposition into spatially grounded document understanding. ADOPD 2026 enriches page anchors inherited from ADOPD 2024 dataset with human-cleaned captions, semantic tags, and generated chain-of-thought (CoT) traces grounded to document regions. Instead of treating boxes, masks, and tags as independent supervision signals, we cast text blocks, visual entities, semantic labels, bounding boxes, and polygon masks as a shared vocabulary of visual anchors. This representation supports three connected capabilities. First, region-level semantic tagging asks models to identify document element types from both page context and local appearance, revealing long-tail semantic failures that standard layout benchmarks often hide. Second, unified vision-language grounding generates text regions and visual entities together with coordinates or polygonal outlines, transforming detection and segmentation outputs into structured anchors that can be reused by downstream reasoning systems. Third, current state-of-the-art models still struggle with dense counting tasks evaluated on DocCount, a benchmark derived from ADOPD 2026, highlighting the need for the Thinking-with-Anchors pipeline in document semantic understanding. By connecting page decomposition to verifiable visual-anchor reasoning, ADOPD 2026 provides a task framework that moves document understanding beyond localization toward anchor-grounded document intelligence.

  • 16 authors
·
Aug 4

Dual Structure-Aware Image Filterings for Semi-supervised Medical Image Segmentation

Semi-supervised image segmentation has attracted great attention recently. The key is how to leverage unlabeled images in the training process. Most methods maintain consistent predictions of the unlabeled images under variations (e.g., adding noise/perturbations, or creating alternative versions) in the image and/or model level. In most image-level variation, medical images often have prior structure information, which has not been well explored. In this paper, we propose novel dual structure-aware image filterings (DSAIF) as the image-level variations for semi-supervised medical image segmentation. Motivated by connected filtering that simplifies image via filtering in structure-aware tree-based image representation, we resort to the dual contrast invariant Max-tree and Min-tree representation. Specifically, we propose a novel connected filtering that removes topologically equivalent nodes (i.e. connected components) having no siblings in the Max/Min-tree. This results in two filtered images preserving topologically critical structure. Applying the proposed DSAIF to mutually supervised networks decreases the consensus of their erroneous predictions on unlabeled images. This helps to alleviate the confirmation bias issue of overfitting to noisy pseudo labels of unlabeled images, and thus effectively improves the segmentation performance. Extensive experimental results on three benchmark datasets demonstrate that the proposed method significantly/consistently outperforms some state-of-the-art methods. The source codes will be publicly available.

  • 7 authors
·
Dec 12, 2023

TopoLoRA-SAM: Topology-Aware Parameter-Efficient Adaptation of Foundation Segmenters for Thin-Structure and Cross-Domain Binary Semantic Segmentation

Foundation segmentation models such as the Segment Anything Model (SAM) exhibit strong zero-shot generalization through large-scale pretraining, but adapting them to domain-specific semantic segmentation remains challenging, particularly for thin structures (e.g., retinal vessels) and noisy modalities (e.g., SAR imagery). Full fine-tuning is computationally expensive and risks catastrophic forgetting. We propose TopoLoRA-SAM, a topology-aware and parameter-efficient adaptation framework for binary semantic segmentation. TopoLoRA-SAM injects Low-Rank Adaptation (LoRA) into the frozen ViT encoder, augmented with a lightweight spatial convolutional adapter and optional topology-aware supervision via differentiable clDice. We evaluate our approach on five benchmarks spanning retinal vessel segmentation (DRIVE, STARE, CHASE\_DB1), polyp segmentation (Kvasir-SEG), and SAR sea/land segmentation (SL-SSDD), comparing against U-Net, DeepLabV3+, SegFormer, and Mask2Former. TopoLoRA-SAM achieves the best retina-average Dice and the best overall average Dice across datasets, while training only 5.2\% of model parameters (sim4.9M). On the challenging CHASE\_DB1 dataset, our method substantially improves segmentation accuracy and robustness, demonstrating that topology-aware parameter-efficient adaptation can match or exceed fully fine-tuned specialist models. Code is available at : https://github.com/salimkhazem/Seglab.git

Talan Talan
·
Jan 5

TotalSegmentator: robust segmentation of 104 anatomical structures in CT images

We present a deep learning segmentation model that can automatically and robustly segment all major anatomical structures in body CT images. In this retrospective study, 1204 CT examinations (from the years 2012, 2016, and 2020) were used to segment 104 anatomical structures (27 organs, 59 bones, 10 muscles, 8 vessels) relevant for use cases such as organ volumetry, disease characterization, and surgical or radiotherapy planning. The CT images were randomly sampled from routine clinical studies and thus represent a real-world dataset (different ages, pathologies, scanners, body parts, sequences, and sites). The authors trained an nnU-Net segmentation algorithm on this dataset and calculated Dice similarity coefficients (Dice) to evaluate the model's performance. The trained algorithm was applied to a second dataset of 4004 whole-body CT examinations to investigate age dependent volume and attenuation changes. The proposed model showed a high Dice score (0.943) on the test set, which included a wide range of clinical data with major pathologies. The model significantly outperformed another publicly available segmentation model on a separate dataset (Dice score, 0.932 versus 0.871, respectively). The aging study demonstrated significant correlations between age and volume and mean attenuation for a variety of organ groups (e.g., age and aortic volume; age and mean attenuation of the autochthonous dorsal musculature). The developed model enables robust and accurate segmentation of 104 anatomical structures. The annotated dataset (https://doi.org/10.5281/zenodo.6802613) and toolkit (https://www.github.com/wasserth/TotalSegmentator) are publicly available.

  • 12 authors
·
Aug 11, 2022

FISBe: A real-world benchmark dataset for instance segmentation of long-range thin filamentous structures

Instance segmentation of neurons in volumetric light microscopy images of nervous systems enables groundbreaking research in neuroscience by facilitating joint functional and morphological analyses of neural circuits at cellular resolution. Yet said multi-neuron light microscopy data exhibits extremely challenging properties for the task of instance segmentation: Individual neurons have long-ranging, thin filamentous and widely branching morphologies, multiple neurons are tightly inter-weaved, and partial volume effects, uneven illumination and noise inherent to light microscopy severely impede local disentangling as well as long-range tracing of individual neurons. These properties reflect a current key challenge in machine learning research, namely to effectively capture long-range dependencies in the data. While respective methodological research is buzzing, to date methods are typically benchmarked on synthetic datasets. To address this gap, we release the FlyLight Instance Segmentation Benchmark (FISBe) dataset, the first publicly available multi-neuron light microscopy dataset with pixel-wise annotations. In addition, we define a set of instance segmentation metrics for benchmarking that we designed to be meaningful with regard to downstream analyses. Lastly, we provide three baselines to kick off a competition that we envision to both advance the field of machine learning regarding methodology for capturing long-range data dependencies, and facilitate scientific discovery in basic neuroscience.

  • 9 authors
·
Mar 29, 2024

Asymmetric Paired-Annotation Learning for Multi-Structure ULF Pediatric Brain MRI Segmentation

Portable ultra-low-field (ULF) MRI can expand access to pediatric neuroimaging, but segmentation at 0.064 T remains challenging because anatomical boundaries are weakly delineated, small structures may be only partially visible, and high-field references can be locally misregistered. The LISA 2026 Challenge provides two non-equivalent annotations reflecting different sources of anatomical evidence: a highfield-derived (HF) mask defining the scored target and a low-field-edited (LF) mask aligned with visible ULF anatomy. In this challenge report, we describe AURA, an nnU-Net-based asymmetric supervision strategy that treats these annotations as distinct observations rather than interchangeable ground truths. AURA anchors training to the HF mask and incorporates the LF mask through a bounded reliability gate based on label disagreement, boundaries, predictive uncertainty, class reliability, and training stage. On a 16-case development split, the HF-supervised baseline, AURA, and their ensemble achieved Dice scores of 0.7984, 0.7950, and 0.7988, respectively, while the ensemble achieved an HD95 of 1.8892 and an ASSD of 0.7855. These results provide a preliminary evaluation of AURA within the LISA 2026 Challenge and motivate further assessment on the hidden test set and external ULF cohorts. Our code and pretrained models are available at https://github.com/minhdang050806/ A-nnU-Net-based-asymmetric-supervision-strategy.

  • 7 authors
·
Sep 1

From Density to Geometry: YOLOv8 Instance Segmentation for Reverse Engineering of Optimized Structures

This paper introduces YOLOv8-TO, a novel approach for reverse engineering of topology-optimized structures into interpretable geometric parameters using the YOLOv8 instance segmentation model. Density-based topology optimization methods require post-processing to convert the optimal density distribution into a parametric representation for design exploration and integration with CAD tools. Traditional methods such as skeletonization struggle with complex geometries and require manual intervention. YOLOv8-TO addresses these challenges by training a custom YOLOv8 model to automatically detect and reconstruct structural components from binary density distributions. The model is trained on a diverse dataset of both optimized and random structures generated using the Moving Morphable Components method. A custom reconstruction loss function based on the dice coefficient of the predicted geometry is used to train the new regression head of the model via self-supervised learning. The method is evaluated on test sets generated from different topology optimization methods, including out-of-distribution samples, and compared against a skeletonization approach. Results show that YOLOv8-TO significantly outperforms skeletonization in reconstructing visually and structurally similar designs. The method showcases an average improvement of 13.84% in the Dice coefficient, with peak enhancements reaching 20.78%. The method demonstrates good generalization to complex geometries and fast inference times, making it suitable for integration into design workflows using regular workstations. Limitations include the sensitivity to non-max suppression thresholds. YOLOv8-TO represents a significant advancement in topology optimization post-processing, enabling efficient and accurate reverse engineering of optimized structures for design exploration and manufacturing.

  • 4 authors
·
Apr 29, 2024

Decoding with Structured Awareness: Integrating Directional, Frequency-Spatial, and Structural Attention for Medical Image Segmentation

To address the limitations of Transformer decoders in capturing edge details, recognizing local textures and modeling spatial continuity, this paper proposes a novel decoder framework specifically designed for medical image segmentation, comprising three core modules. First, the Adaptive Cross-Fusion Attention (ACFA) module integrates channel feature enhancement with spatial attention mechanisms and introduces learnable guidance in three directions (planar, horizontal, and vertical) to enhance responsiveness to key regions and structural orientations. Second, the Triple Feature Fusion Attention (TFFA) module fuses features from Spatial, Fourier and Wavelet domains, achieving joint frequency-spatial representation that strengthens global dependency and structural modeling while preserving local information such as edges and textures, making it particularly effective in complex and blurred boundary scenarios. Finally, the Structural-aware Multi-scale Masking Module (SMMM) optimizes the skip connections between encoder and decoder by leveraging multi-scale context and structural saliency filtering, effectively reducing feature redundancy and improving semantic interaction quality. Working synergistically, these modules not only address the shortcomings of traditional decoders but also significantly enhance performance in high-precision tasks such as tumor segmentation and organ boundary extraction, improving both segmentation accuracy and model generalization. Experimental results demonstrate that this framework provides an efficient and practical solution for medical image segmentation.

  • 3 authors
·
Dec 5, 2025

Better, Stronger, Faster, and Broader: Structured All-Mask Prediction for MLLM-Based Segmentation

MLLM-based segmentation faces a core segmentation trilemma: high segmentation performance, preserved dialogue ability, and fast inference. Embedding-prediction methods may disrupt language modeling through pixel-level objectives, whereas next-token generation is inefficient for dense masks. We propose All-Mask Prediction, decoupling autoregressive dialogue from non-autoregressive mask prediction. Its binary instantiation, STAMP (Simultaneous Textual All-Mask Prediction), emits an in-vocabulary <SEG> trigger, fuses image-aligned mask tokens with corresponding patch features, and uses hybrid attention to classify all tokens as foreground or background in one pass. It thereby combines strong referring and reasoning segmentation with preserved multimodal ability and efficient inference. However, binary masks cannot retain multiple semantic or instance identities without repeated target-specific predictions. We therefore propose Structured All-Mask Prediction and develop STAMPlus. It generates a target list with explicit IDs and optional boxes, binds these IDs to a shared multi-class mask space, and jointly predicts all targets in one non-autoregressive pass. A single unified checkpoint retains STAMP's referring and reasoning capabilities while extending to open-vocabulary semantic, instance-aware, and remote-sensing small-target segmentation, where high-resolution mask-token scaling preserves finer spatial evidence. Across these settings, STAMPlus achieves state-of-the-art segmentation performance, preserves general multimodal instruction following, and reduces 12-category latency from 13.50s for repeated STAMP inference to 5.16s. Further analyses show that accurate target cues improve segmentation and learned spatial grounding benefits look-twice reasoning. Overall, STAMPlus resolves the trilemma beyond single-target prediction.

Segmentation and Processing of German Court Decisions from Open Legal Data

The availability of structured legal data is important for advancing Natural Language Processing (NLP) techniques for the German legal system. One of the most widely used datasets, Open Legal Data, provides a large-scale collection of German court decisions. While the metadata in this raw dataset is consistently structured, the decision texts themselves are inconsistently formatted and often lack clearly marked sections. Reliable separation of these sections is important not only for rhetorical role classification but also for downstream tasks such as retrieval and citation analysis. In this work, we introduce a cleaned and sectioned dataset of 251,038 German court decisions derived from the official Open Legal Data dataset. We systematically separated three important sections in German court decisions, namely Tenor (operative part of the decision), Tatbestand (facts of the case), and Entscheidungsgründe (judicial reasoning), which are often inconsistently represented in the original dataset. To ensure the reliability of our extraction process, we used Cochran's formula with a 95% confidence level and a 5% margin of error to draw a statistically representative random sample of 384 cases, and manually verified that all three sections were correctly identified. We also extracted the Rechtsmittelbelehrung (appeal notice) as a separate field, since it is a procedural instruction and not part of the decision itself. The resulting corpus is publicly available in the JSONL format, making it an accessible resource for further research on the German legal system.

  • 4 authors
·
Jan 4

SegTME-UNI2: A Foundation Model-Based Framework for Generalisable Multiclass Cell Segmentation and LLM-Driven Tumour Microenvironment Characterisation in Histopathology

Characterising the tumour microenvironment (TME) from routine H&E-stained histology images requires simultaneous cell segmentation, feature extraction, and interpretable clinical reporting. We present SEGTME-UNI2, a unified framework addressing these requirements. Its core is UNI2-UPERHOVER, a dual-head segmentation model pairing the UNI2-H pathology foundation model (ViT-Giant, pretrained on >100M tiles from 100K slides) with two parallel UperNet decoders: one for six-class semantic segmentation and one for horizontal-vertical gradient regression enabling watershed-based nuclear instance separation. To address the lack of pixel-level annotations in large real-world repositories, UNI2-UPERHOVER undergoes a three-stage progressive pseudo-label curriculum. Each stage trains a fresh model without weight transfer, driving improvement entirely via increased pseudo-label quality: Stage 1: Uses human-annotated PanNuke (7,901 images, 189,744 nuclei, 0.25 um/pixel). Stage 2: Uses entropy-filtered pseudo-labels from the Stage 1 model on 271,711 TCGA-UT scale-0 patches (0.5 um/pixel). Stage 3: Uses pseudo-labels from the Stage 2 model on all 1,608,060 TCGA-UT patches across six resolution scales (0.5-1.0 um/pixel). Segmentation outputs feed a structured TME feature extraction pipeline computing 20+ per-patch compositional, morphological, spatial entropy, and intercellular distance metrics. These are encoded as JSON and passed to a fine-tuned NVIDIA BioNeMo GPT model to generate clinically interpretable TME narratives. Preliminary validation on held-out PanNuke and TCGA-UT partitions demonstrates framework feasibility and internal consistency. The pseudo-labelled TCGA-UT dataset and UNI2-UPERHOVER checkpoint are publicly released to support large-scale TME profiling and spatial biology research.

  • 6 authors
·
Jun 15

SegCol Challenge: Semantic Segmentation for Tools and Fold Edges in Colonoscopy data

Improving the reliability and completeness of colonoscopic inspection is critical for reducing missed lesions and improving colorectal cancer prevention. Reliable scene understanding is essential for navigation, reconstruction, and assessment of inspection completeness. Anatomical structures such as mucosal folds provide stable geometric cues for endoscope localization, while surgical instruments introduce dynamic occlusions that complicate visual interpretation. However, existing gastrointestinal endoscopy datasets largely focus on disease detection or artifact segmentation, leaving a gap in precise annotations of structural landmarks and instruments. We introduce SegCol, a dataset and benchmark for semantic segmentation of colon fold edges and surgical instruments derived from the EndoMapper dataset. SegCol provides manually annotated pixel-level masks for three instrument classes and thin fold-edge structures across temporally consistent image sequences. It forms the basis of the SegCol Challenge, organized as part of the EndoVis Challenge at MICCAI 2024, evaluating both supervised segmentation and annotation-efficient active learning. We further study segmentation metrics, including Dice, ODS/OIS, AP, and CLDice, under structural perturbations and different object geometries, and analyze participating methods, architectural choices, and active learning strategies. Our findings show that metric behavior strongly depends on target structure, highlighting the need for carefully selected evaluation protocols in endoscopic segmentation. Details are available at https://www.synapse.org/Synapse:syn54124209/wiki/626563, and code at https://github.com/surgical-vision/segcol_challenge.

  • 10 authors
·
Dec 20, 2024

Semantic Amodal Segmentation

Common visual recognition tasks such as classification, object detection, and semantic segmentation are rapidly reaching maturity, and given the recent rate of progress, it is not unreasonable to conjecture that techniques for many of these problems will approach human levels of performance in the next few years. In this paper we look to the future: what is the next frontier in visual recognition? We offer one possible answer to this question. We propose a detailed image annotation that captures information beyond the visible pixels and requires complex reasoning about full scene structure. Specifically, we create an amodal segmentation of each image: the full extent of each region is marked, not just the visible pixels. Annotators outline and name all salient regions in the image and specify a partial depth order. The result is a rich scene structure, including visible and occluded portions of each region, figure-ground edge information, semantic labels, and object overlap. We create two datasets for semantic amodal segmentation. First, we label 500 images in the BSDS dataset with multiple annotators per image, allowing us to study the statistics of human annotations. We show that the proposed full scene annotation is surprisingly consistent between annotators, including for regions and edges. Second, we annotate 5000 images from COCO. This larger dataset allows us to explore a number of algorithmic ideas for amodal segmentation and depth ordering. We introduce novel metrics for these tasks, and along with our strong baselines, define concrete new challenges for the community.

  • 4 authors
·
Sep 3, 2015

SPOCKMIP: Segmentation of Vessels in MRAs with Enhanced Continuity using Maximum Intensity Projection as Loss

Identification of vessel structures of different sizes in biomedical images is crucial in the diagnosis of many neurodegenerative diseases. However, the sparsity of good-quality annotations of such images makes the task of vessel segmentation challenging. Deep learning offers an efficient way to segment vessels of different sizes by learning their high-level feature representations and the spatial continuity of such features across dimensions. Semi-supervised patch-based approaches have been effective in identifying small vessels of one to two voxels in diameter. This study focuses on improving the segmentation quality by considering the spatial correlation of the features using the Maximum Intensity Projection~(MIP) as an additional loss criterion. Two methods are proposed with the incorporation of MIPs of label segmentation on the single~(z-axis) and multiple perceivable axes of the 3D volume. The proposed MIP-based methods produce segmentations with improved vessel continuity, which is evident in visual examinations of ROIs. Patch-based training is improved by introducing an additional loss term, MIP loss, to penalise the predicted discontinuity of vessels. A training set of 14 volumes is selected from the StudyForrest dataset comprising of 18 7-Tesla 3D Time-of-Flight~(ToF) Magnetic Resonance Angiography (MRA) images. The generalisation performance of the method is evaluated using the other unseen volumes in the dataset. It is observed that the proposed method with multi-axes MIP loss produces better quality segmentations with a median Dice of 80.245 pm 0.129. Also, the method with single-axis MIP loss produces segmentations with a median Dice of 79.749 pm 0.109. Furthermore, a visual comparison of the ROIs in the predicted segmentation reveals a significant improvement in the continuity of the vessels when MIP loss is incorporated into training.

  • 8 authors
·
Jul 11, 2024

Full-scale Representation Guided Network for Retinal Vessel Segmentation

The U-Net architecture and its variants have remained state-of-the-art (SOTA) for retinal vessel segmentation over the past decade. In this study, we introduce a Full-Scale Guided Network (FSG-Net), where a novel feature representation module using modernized convolution blocks effectively captures full-scale structural information, while a guided convolution block subsequently refines this information. Specifically, we introduce an attention-guided filter within the guided convolution block, leveraging its similarity to unsharp masking to enhance fine vascular structures. Passing full-scale information to the attention block facilitates the generation of more contextually relevant attention maps, which are then passed to the attention-guided filter, providing further refinement to the segmentation performance. The structure preceding the guided convolution block can be replaced by any U-Net variant, ensuring flexibility and scalability across various segmentation tasks. For a fair comparison, we re-implemented recent studies available in public repositories to evaluate their scalability and reproducibility. Our experiments demonstrate that, despite its compact architecture, FSG-Net delivers performance competitive with SOTA methods across multiple public datasets. Ablation studies further demonstrate that each proposed component meaningfully contributes to this competitive performance. Our code is available on https://github.com/ZombaSY/FSG-Net-pytorch.

  • 3 authors
·
Jan 31, 2025

SGDC: Structurally-Guided Dynamic Convolution for Medical Image Segmentation

Spatially variant dynamic convolution provides a principled approach of integrating spatial adaptivity into deep neural networks. However, mainstream designs in medical segmentation commonly generate dynamic kernels through average pooling, which implicitly collapses high-frequency spatial details into a coarse, spatially-compressed representation, leading to over-smoothed predictions that degrade the fidelity of fine-grained clinical structures. To address this limitation, we propose a novel Structure-Guided Dynamic Convolution (SGDC) mechanism, which leverages an explicitly supervised structure-extraction branch to guide the generation of dynamic kernels and gating signals for structure-aware feature modulation. Specifically, the high-fidelity boundary information from this auxiliary branch is fused with semantic features to enable spatially-precise feature modulation. By replacing context aggregation with pixel-wise structural guidance, the proposed design effectively prevents the information loss introduced by average pooling. Experimental results show that SGDC achieves state-of-the-art performance on ISIC 2016, PH2, ISIC 2018, and CoNIC datasets, delivering superior boundary fidelity by reducing the Hausdorff Distance (HD95) by 2.05, and providing consistent IoU gains of 0.99\%-1.49\% over pooling-based baselines. Moreover, the mechanism exhibits strong potential for extension to other fine-grained, structure-sensitive vision tasks, such as small-object detection, offering a principled solution for preserving structural integrity in medical image analysis. To facilitate reproducibility and encourage further research, the implementation code for both our SGE and SGDC modules has been is publicly released at https://github.com/solstice0621/SGDC.

  • 3 authors
·
Feb 26 2

SEMv2: Table Separation Line Detection Based on Instance Segmentation

Table structure recognition is an indispensable element for enabling machines to comprehend tables. Its primary purpose is to identify the internal structure of a table. Nevertheless, due to the complexity and diversity of their structure and style, it is highly challenging to parse the tabular data into a structured format that machines can comprehend. In this work, we adhere to the principle of the split-and-merge based methods and propose an accurate table structure recognizer, termed SEMv2 (SEM: Split, Embed and Merge). Unlike the previous works in the ``split'' stage, we aim to address the table separation line instance-level discrimination problem and introduce a table separation line detection strategy based on conditional convolution. Specifically, we design the ``split'' in a top-down manner that detects the table separation line instance first and then dynamically predicts the table separation line mask for each instance. The final table separation line shape can be accurately obtained by processing the table separation line mask in a row-wise/column-wise manner. To comprehensively evaluate the SEMv2, we also present a more challenging dataset for table structure recognition, dubbed iFLYTAB, which encompasses multiple style tables in various scenarios such as photos, scanned documents, etc. Extensive experiments on publicly available datasets (e.g. SciTSR, PubTabNet and iFLYTAB) demonstrate the efficacy of our proposed approach. The code and iFLYTAB dataset are available at https://github.com/ZZR8066/SEMv2.

  • 9 authors
·
Jan 11, 2024

NuClick: A Deep Learning Framework for Interactive Segmentation of Microscopy Images

Object segmentation is an important step in the workflow of computational pathology. Deep learning based models generally require large amount of labeled data for precise and reliable prediction. However, collecting labeled data is expensive because it often requires expert knowledge, particularly in medical imaging domain where labels are the result of a time-consuming analysis made by one or more human experts. As nuclei, cells and glands are fundamental objects for downstream analysis in computational pathology/cytology, in this paper we propose a simple CNN-based approach to speed up collecting annotations for these objects which requires minimum interaction from the annotator. We show that for nuclei and cells in histology and cytology images, one click inside each object is enough for NuClick to yield a precise annotation. For multicellular structures such as glands, we propose a novel approach to provide the NuClick with a squiggle as a guiding signal, enabling it to segment the glandular boundaries. These supervisory signals are fed to the network as auxiliary inputs along with RGB channels. With detailed experiments, we show that NuClick is adaptable to the object scale, robust against variations in the user input, adaptable to new domains, and delivers reliable annotations. An instance segmentation model trained on masks generated by NuClick achieved the first rank in LYON19 challenge. As exemplar outputs of our framework, we are releasing two datasets: 1) a dataset of lymphocyte annotations within IHC images, and 2) a dataset of segmented WBCs in blood smear images.

  • 4 authors
·
May 29, 2020

Segmentation and Vascular Vectorization for Coronary Artery by Geometry-based Cascaded Neural Network

Segmentation of the coronary artery is an important task for the quantitative analysis of coronary computed tomography angiography (CCTA) images and is being stimulated by the field of deep learning. However, the complex structures with tiny and narrow branches of the coronary artery bring it a great challenge. Coupled with the medical image limitations of low resolution and poor contrast, fragmentations of segmented vessels frequently occur in the prediction. Therefore, a geometry-based cascaded segmentation method is proposed for the coronary artery, which has the following innovations: 1) Integrating geometric deformation networks, we design a cascaded network for segmenting the coronary artery and vectorizing results. The generated meshes of the coronary artery are continuous and accurate for twisted and sophisticated coronary artery structures, without fragmentations. 2) Different from mesh annotations generated by the traditional marching cube method from voxel-based labels, a finer vectorized mesh of the coronary artery is reconstructed with the regularized morphology. The novel mesh annotation benefits the geometry-based segmentation network, avoiding bifurcation adhesion and point cloud dispersion in intricate branches. 3) A dataset named CCA-200 is collected, consisting of 200 CCTA images with coronary artery disease. The ground truths of 200 cases are coronary internal diameter annotations by professional radiologists. Extensive experiments verify our method on our collected dataset CCA-200 and public ASOCA dataset, with a Dice of 0.778 on CCA-200 and 0.895 on ASOCA, showing superior results. Especially, our geometry-based model generates an accurate, intact and smooth coronary artery, devoid of any fragmentations of segmented vessels.

  • 6 authors
·
May 7, 2023

Learning Structured Output Representations from Attributes using Deep Conditional Generative Models

Structured output representation is a generative task explored in computer vision that often times requires the mapping of low dimensional features to high dimensional structured outputs. Losses in complex spatial information in deterministic approaches such as Convolutional Neural Networks (CNN) lead to uncertainties and ambiguous structures within a single output representation. A probabilistic approach through deep Conditional Generative Models (CGM) is presented by Sohn et al. in which a particular model known as the Conditional Variational Auto-encoder (CVAE) is introduced and explored. While the original paper focuses on the task of image segmentation, this paper adopts the CVAE framework for the task of controlled output representation through attributes. This approach allows us to learn a disentangled multimodal prior distribution, resulting in more controlled and robust approach to sample generation. In this work we recreate the CVAE architecture and train it on images conditioned on various attributes obtained from two image datasets; the Large-scale CelebFaces Attributes (CelebA) dataset and the Caltech-UCSD Birds (CUB-200-2011) dataset. We attempt to generate new faces with distinct attributes such as hair color and glasses, as well as different bird species samples with various attributes. We further introduce strategies for improving generalized sample generation by applying a weighted term to the variational lower bound.

  • 1 authors
·
Apr 30, 2023

Improving Long Document Topic Segmentation Models With Enhanced Coherence Modeling

Topic segmentation is critical for obtaining structured documents and improving downstream tasks such as information retrieval. Due to its ability of automatically exploring clues of topic shift from abundant labeled data, recent supervised neural models have greatly promoted the development of long document topic segmentation, but leaving the deeper relationship between coherence and topic segmentation underexplored. Therefore, this paper enhances the ability of supervised models to capture coherence from both logical structure and semantic similarity perspectives to further improve the topic segmentation performance, proposing Topic-aware Sentence Structure Prediction (TSSP) and Contrastive Semantic Similarity Learning (CSSL). Specifically, the TSSP task is proposed to force the model to comprehend structural information by learning the original relations between adjacent sentences in a disarrayed document, which is constructed by jointly disrupting the original document at topic and sentence levels. Moreover, we utilize inter- and intra-topic information to construct contrastive samples and design the CSSL objective to ensure that the sentences representations in the same topic have higher similarity, while those in different topics are less similar. Extensive experiments show that the Longformer with our approach significantly outperforms old state-of-the-art (SOTA) methods. Our approach improve F_1 of old SOTA by 3.42 (73.74 -> 77.16) and reduces P_k by 1.11 points (15.0 -> 13.89) on WIKI-727K and achieves an average relative reduction of 4.3% on P_k on WikiSection. The average relative P_k drop of 8.38% on two out-of-domain datasets also demonstrates the robustness of our approach.

  • 6 authors
·
Oct 18, 2023

Segmentation with Noisy Labels via Spatially Correlated Distributions

In semantic segmentation, the accuracy of models heavily depends on the high-quality annotations. However, in many practical scenarios such as medical imaging and remote sensing, obtaining true annotations is not straightforward and usually requires significant human labor. Relying on human labor often introduces annotation errors, including mislabeling, omissions, and inconsistency between annotators. In the case of remote sensing, differences in procurement time can lead to misaligned ground truth annotations. These label errors are not independently distributed, and instead usually appear in spatially connected regions where adjacent pixels are more likely to share the same errors. To address these issues, we propose an approximate Bayesian estimation based on a probabilistic model that assumes training data includes label errors, incorporating the tendency for these errors to occur with spatial correlations between adjacent pixels. Bayesian inference requires computing the posterior distribution of label errors, which becomes intractable when spatial correlations are present. We represent the correlation of label errors between adjacent pixels through a Gaussian distribution whose covariance is structured by a Kac-Murdock-Szeg\"{o} (KMS) matrix, solving the computational challenges. Through experiments on multiple segmentation tasks, we confirm that leveraging the spatial correlation of label errors significantly improves performance. Notably, in specific tasks such as lung segmentation, the proposed method achieves performance comparable to training with clean labels under moderate noise levels. Code is available at https://github.com/pfnet-research/Bayesian_SpatialCorr.

  • 3 authors
·
Apr 20, 2025

Classification and understanding of cloud structures via satellite images with EfficientUNet

Climate change has been a common interest and the forefront of crucial political discussion and decision-making for many years. Shallow clouds play a significant role in understanding the Earth's climate, but they are challenging to interpret and represent in a climate model. By classifying these cloud structures, there is a better possibility of understanding the physical structures of the clouds, which would improve the climate model generation, resulting in a better prediction of climate change or forecasting weather update. Clouds organise in many forms, which makes it challenging to build traditional rule-based algorithms to separate cloud features. In this paper, classification of cloud organization patterns was performed using a new scaled-up version of Convolutional Neural Network (CNN) named as EfficientNet as the encoder and UNet as decoder where they worked as feature extractor and reconstructor of fine grained feature map and was used as a classifier, which will help experts to understand how clouds will shape the future climate. By using a segmentation model in a classification task, it was shown that with a good encoder alongside UNet, it is possible to obtain good performance from this dataset. Dice coefficient has been used for the final evaluation metric, which gave the score of 66.26\% and 66.02\% for public and private (test set) leaderboard on Kaggle competition respectively.

  • 2 authors
·
Jul 8, 2021

Token Contrast for Weakly-Supervised Semantic Segmentation

Weakly-Supervised Semantic Segmentation (WSSS) using image-level labels typically utilizes Class Activation Map (CAM) to generate the pseudo labels. Limited by the local structure perception of CNN, CAM usually cannot identify the integral object regions. Though the recent Vision Transformer (ViT) can remedy this flaw, we observe it also brings the over-smoothing issue, \ie, the final patch tokens incline to be uniform. In this work, we propose Token Contrast (ToCo) to address this issue and further explore the virtue of ViT for WSSS. Firstly, motivated by the observation that intermediate layers in ViT can still retain semantic diversity, we designed a Patch Token Contrast module (PTC). PTC supervises the final patch tokens with the pseudo token relations derived from intermediate layers, allowing them to align the semantic regions and thus yield more accurate CAM. Secondly, to further differentiate the low-confidence regions in CAM, we devised a Class Token Contrast module (CTC) inspired by the fact that class tokens in ViT can capture high-level semantics. CTC facilitates the representation consistency between uncertain local regions and global objects by contrasting their class tokens. Experiments on the PASCAL VOC and MS COCO datasets show the proposed ToCo can remarkably surpass other single-stage competitors and achieve comparable performance with state-of-the-art multi-stage methods. Code is available at https://github.com/rulixiang/ToCo.

  • 4 authors
·
Mar 2, 2023

Complexity in Complexity: Understanding Visual Complexity Through Structure, Color, and Surprise

Understanding how humans perceive visual complexity is a key area of study in visual cognition. Previous approaches to modeling visual complexity assessments have often resulted in intricate, difficult-to-interpret algorithms that employ numerous features or sophisticated deep learning architectures. While these complex models achieve high performance on specific datasets, they often sacrifice interpretability, making it challenging to understand the factors driving human perception of complexity. Recently (Shen, et al. 2024) proposed an interpretable segmentation-based model that accurately predicted complexity across various datasets, supporting the idea that complexity can be explained simply. In this work, we investigate the failure of their model to capture structural, color and surprisal contributions to complexity. To this end, we propose Multi-Scale Sobel Gradient (MSG) which measures spatial intensity variations, Multi-Scale Unique Color (MUC) which quantifies colorfulness across multiple scales, and surprise scores generated using a Large Language Model. We test our features on existing benchmarks and a novel dataset (Surprising Visual Genome) containing surprising images from Visual Genome. Our experiments demonstrate that modeling complexity accurately is not as simple as previously thought, requiring additional perceptual and semantic factors to address dataset biases. Our model improves predictive performance while maintaining interpretability, offering deeper insights into how visual complexity is perceived and assessed. Our code, analysis and data are available at https://github.com/Complexity-Project/Complexity-in-Complexity.

  • 4 authors
·
Jan 27, 2025

Exploring Transfer Learning in Medical Image Segmentation using Vision-Language Models

Medical image segmentation allows quantifying target structure size and shape, aiding in disease diagnosis, prognosis, surgery planning, and comprehension.Building upon recent advancements in foundation Vision-Language Models (VLMs) from natural image-text pairs, several studies have proposed adapting them to Vision-Language Segmentation Models (VLSMs) that allow using language text as an additional input to segmentation models. Introducing auxiliary information via text with human-in-the-loop prompting during inference opens up unique opportunities, such as open vocabulary segmentation and potentially more robust segmentation models against out-of-distribution data. Although transfer learning from natural to medical images has been explored for image-only segmentation models, the joint representation of vision-language in segmentation problems remains underexplored. This study introduces the first systematic study on transferring VLSMs to 2D medical images, using carefully curated 11 datasets encompassing diverse modalities and insightful language prompts and experiments. Our findings demonstrate that although VLSMs show competitive performance compared to image-only models for segmentation after finetuning in limited medical image datasets, not all VLSMs utilize the additional information from language prompts, with image features playing a dominant role. While VLSMs exhibit enhanced performance in handling pooled datasets with diverse modalities and show potential robustness to domain shifts compared to conventional segmentation models, our results suggest that novel approaches are required to enable VLSMs to leverage the various auxiliary information available through language prompts. The code and datasets are available at https://github.com/naamiinepal/medvlsm.

  • 6 authors
·
Aug 15, 2023

MedCRP-CL: Continual Medical Image Segmentation via Bayesian Nonparametric Semantic Modality Discovery

Medical image segmentation faces a fundamental challenge in continual learning: data arrives sequentially from heterogeneous sources, yet effective continual learning requires discovering which tasks share sufficient structure to benefit from joint learning. Existing methods either apply uniform constraints across all tasks, causing catastrophic forgetting when tasks conflict, or require predefined task groupings that cannot anticipate future task diversity. We introduce MedCRP-CL, a framework that performs online task structure discovery and structure-aware continual learning. Leveraging the Chinese Restaurant Process (CRP), our method dynamically infers task groupings from clinical text prompts as tasks arrive, without requiring predefined cluster counts or access to future tasks. We term these discovered groupings semantic modalities, as they capture finer-grained structure than physical imaging modalities by integrating anatomical region and pathological context. Guided by this discovered structure, we maintain semantic modality-specific LoRA adapters regularized by intra-modality EWC, ensuring parameter isolation across dissimilar task groups while facilitating knowledge transfer within similar ones. The framework is also replay-free, storing only aggregate statistics rather than raw patient data. Experiments on 16 medical segmentation tasks across four imaging modalities demonstrate that MedCRP-CL achieves 73.3% Dice score with only 4.1% forgetting, outperforming the best baseline by 8.0% while requiring 6times fewer parameters. Code is available at https://github.com/zygao930/MedCRP-CL.

  • 1 authors
·
Aug 3

CrackNex: a Few-shot Low-light Crack Segmentation Model Based on Retinex Theory for UAV Inspections

Routine visual inspections of concrete structures are imperative for upholding the safety and integrity of critical infrastructure. Such visual inspections sometimes happen under low-light conditions, e.g., checking for bridge health. Crack segmentation under such conditions is challenging due to the poor contrast between cracks and their surroundings. However, most deep learning methods are designed for well-illuminated crack images and hence their performance drops dramatically in low-light scenes. In addition, conventional approaches require many annotated low-light crack images which is time-consuming. In this paper, we address these challenges by proposing CrackNex, a framework that utilizes reflectance information based on Retinex Theory to help the model learn a unified illumination-invariant representation. Furthermore, we utilize few-shot segmentation to solve the inefficient training data problem. In CrackNex, both a support prototype and a reflectance prototype are extracted from the support set. Then, a prototype fusion module is designed to integrate the features from both prototypes. CrackNex outperforms the SOTA methods on multiple datasets. Additionally, we present the first benchmark dataset, LCSD, for low-light crack segmentation. LCSD consists of 102 well-illuminated crack images and 41 low-light crack images. The dataset and code are available at https://github.com/zy1296/CrackNex.

  • 4 authors
·
Mar 5, 2024

CADS: A Comprehensive Anatomical Dataset and Segmentation for Whole-Body Anatomy in Computed Tomography

Accurate delineation of anatomical structures in volumetric CT scans is crucial for diagnosis and treatment planning. While AI has advanced automated segmentation, current approaches typically target individual structures, creating a fragmented landscape of incompatible models with varying performance and disparate evaluation protocols. Foundational segmentation models address these limitations by providing a holistic anatomical view through a single model. Yet, robust clinical deployment demands comprehensive training data, which is lacking in existing whole-body approaches, both in terms of data heterogeneity and, more importantly, anatomical coverage. In this work, rather than pursuing incremental optimizations in model architecture, we present CADS, an open-source framework that prioritizes the systematic integration, standardization, and labeling of heterogeneous data sources for whole-body CT segmentation. At its core is a large-scale dataset of 22,022 CT volumes with complete annotations for 167 anatomical structures, representing a significant advancement in both scale and coverage, with 18 times more scans than existing collections and 60% more distinct anatomical targets. Building on this diverse dataset, we develop the CADS-model using established architectures for accessible and automated full-body CT segmentation. Through comprehensive evaluation across 18 public datasets and an independent real-world hospital cohort, we demonstrate advantages over SoTA approaches. Notably, thorough testing of the model's performance in segmentation tasks from radiation oncology validates its direct utility for clinical interventions. By making our large-scale dataset, our segmentation models, and our clinical software tool publicly available, we aim to advance robust AI solutions in radiology and make comprehensive anatomical analysis accessible to clinicians and researchers alike.

  • 33 authors
·
Jul 29, 2025

Semantic2Graph: Graph-based Multi-modal Feature Fusion for Action Segmentation in Videos

Video action segmentation have been widely applied in many fields. Most previous studies employed video-based vision models for this purpose. However, they often rely on a large receptive field, LSTM or Transformer methods to capture long-term dependencies within videos, leading to significant computational resource requirements. To address this challenge, graph-based model was proposed. However, previous graph-based models are less accurate. Hence, this study introduces a graph-structured approach named Semantic2Graph, to model long-term dependencies in videos, thereby reducing computational costs and raise the accuracy. We construct a graph structure of video at the frame-level. Temporal edges are utilized to model the temporal relations and action order within videos. Additionally, we have designed positive and negative semantic edges, accompanied by corresponding edge weights, to capture both long-term and short-term semantic relationships in video actions. Node attributes encompass a rich set of multi-modal features extracted from video content, graph structures, and label text, encompassing visual, structural, and semantic cues. To synthesize this multi-modal information effectively, we employ a graph neural network (GNN) model to fuse multi-modal features for node action label classification. Experimental results demonstrate that Semantic2Graph outperforms state-of-the-art methods in terms of performance, particularly on benchmark datasets such as GTEA and 50Salads. Multiple ablation experiments further validate the effectiveness of semantic features in enhancing model performance. Notably, the inclusion of semantic edges in Semantic2Graph allows for the cost-effective capture of long-term dependencies, affirming its utility in addressing the challenges posed by computational resource constraints in video-based vision models.

  • 3 authors
·
Feb 5, 2024

A Unified Framework for Comprehensive Cardiac CT Segmentation and Phenotyping: Human-in-the-Loop Data Annotation, Vision Foundation Model Development, Multicenter Evaluation and Clinical Validation

Comprehensive quantification of cardiac structures from computed tomography (CT) remains limited not by data availability but by the scalability of measurements, which makes routine use impractical. Here we present a unified framework for comprehensive cardiac CT segmentation and phenotyping that combines a human-in-the-loop annotation pipeline, a cardiac CT augmentation technique, and a self-supervised foundation model pre-trained on 60,000 unlabeled cardiac CT scans. Using this approach, we assembled the largest and most comprehensive expert-annotated cardiac CT segmentation dataset to date, comprising 1598 cases and 14 distinct cardiac structures (1000 for training, 598 for the external test set). Across five external datasets, the framework segmented all structures more accurately and comprehensively than existing open-source tools. Self-supervised pre-training improved labeling efficiency, with the most significant gains observed during external evaluation in the low-data regime. Benchmarking across convolutional, transformer, and state-space architectures showed comparable performance, indicating that data quality and pre-training, rather than architecture, drove accuracy. The framework was scaled to population-level phenotyping, with segmented anatomy that carries functionally relevant information about ventricular function and disease severity beyond demographic variables. By openly releasing the largest dataset with human labels, code, model weights, a CT augmentation library, and software, this work provides a reproducible foundation for opportunistic cardiac phenotyping from routinely acquired CT scans.

  • 20 authors
·
Jul 12

StrucPhysVideo: Learning Physical Dynamics from Structured Captions and Robot Actions

Modeling physical dynamics, including how objects move, interact, and change state, is central to video world models for embodied AI. We present StrucPhysVideo, a family of video world models that bridges physics-focused data curation with language- and action-conditioned prediction of scene evolution. Our data pipeline combines motion-aware video segmentation, quality and content filtering, and physical relevance verification with structured annotations of objects, materials, and temporally localized interactions. By disentangling camera motion from object behavior and explicitly describing contact, deformation, and state transitions, the pipeline provides supervision grounded in observable physical events. Building on these data, we introduce StrucPhysVideo-TI2V, a sparse Mixture-of-Experts (MoE) text-image-to-video model trained with a curriculum that progressively emphasizes physical dynamics while retaining general-domain video data. StrucPhysVideo-TI2V achieves state-of-the-art performance on Physics-IQ Verified, scoring 45.5% and outperforming Cosmos3-Super-Image2Video by 2.8 percentage points. Caption ablations across backbones further demonstrate the effectiveness of physics-focused supervision. We further extend StrucPhysVideo-TI2V to StrucPhysVideo-IA2V, an interactive image-action-to-video world model that predicts visual outcomes from robot end-effector commands. Action conditioning, causal autoregressive generation, and few-step distillation enable incremental robot rollouts with only four denoising steps. Together, StrucPhysVideo advances physical dynamics modeling from image- and language-conditioned video prediction toward action-driven interaction.

  • 9 authors
·
Sep 15

SAM-DiffSR: Structure-Modulated Diffusion Model for Image Super-Resolution

Diffusion-based super-resolution (SR) models have recently garnered significant attention due to their potent restoration capabilities. But conventional diffusion models perform noise sampling from a single distribution, constraining their ability to handle real-world scenes and complex textures across semantic regions. With the success of segment anything model (SAM), generating sufficiently fine-grained region masks can enhance the detail recovery of diffusion-based SR model. However, directly integrating SAM into SR models will result in much higher computational cost. In this paper, we propose the SAM-DiffSR model, which can utilize the fine-grained structure information from SAM in the process of sampling noise to improve the image quality without additional computational cost during inference. In the process of training, we encode structural position information into the segmentation mask from SAM. Then the encoded mask is integrated into the forward diffusion process by modulating it to the sampled noise. This adjustment allows us to independently adapt the noise mean within each corresponding segmentation area. The diffusion model is trained to estimate this modulated noise. Crucially, our proposed framework does NOT change the reverse diffusion process and does NOT require SAM at inference. Experimental results demonstrate the effectiveness of our proposed method, showcasing superior performance in suppressing artifacts, and surpassing existing diffusion-based methods by 0.74 dB at the maximum in terms of PSNR on DIV2K dataset. The code and dataset are available at https://github.com/lose4578/SAM-DiffSR.

  • 7 authors
·
Feb 26, 2024 1

Global Rice Multi-Class Segmentation Dataset (RiceSEG): A Comprehensive and Diverse High-Resolution RGB-Annotated Images for the Development and Benchmarking of Rice Segmentation Algorithms

Developing computer vision-based rice phenotyping techniques is crucial for precision field management and accelerating breeding, thereby continuously advancing rice production. Among phenotyping tasks, distinguishing image components is a key prerequisite for characterizing plant growth and development at the organ scale, enabling deeper insights into eco-physiological processes. However, due to the fine structure of rice organs and complex illumination within the canopy, this task remains highly challenging, underscoring the need for a high-quality training dataset. Such datasets are scarce, both due to a lack of large, representative collections of rice field images and the time-intensive nature of annotation. To address this gap, we established the first comprehensive multi-class rice semantic segmentation dataset, RiceSEG. We gathered nearly 50,000 high-resolution, ground-based images from five major rice-growing countries (China, Japan, India, the Philippines, and Tanzania), encompassing over 6,000 genotypes across all growth stages. From these original images, 3,078 representative samples were selected and annotated with six classes (background, green vegetation, senescent vegetation, panicle, weeds, and duckweed) to form the RiceSEG dataset. Notably, the sub-dataset from China spans all major genotypes and rice-growing environments from the northeast to the south. Both state-of-the-art convolutional neural networks and transformer-based semantic segmentation models were used as baselines. While these models perform reasonably well in segmenting background and green vegetation, they face difficulties during the reproductive stage, when canopy structures are more complex and multiple classes are involved. These findings highlight the importance of our dataset for developing specialized segmentation models for rice and other crops.

  • 24 authors
·
Apr 2, 2025

The SAM2-to-SAM3 Gap in the Segment Anything Model Family: Why Prompt-Based Expertise Fails in Concept-Driven Image Segmentation

This paper investigates the fundamental discontinuity between the latest two Segment Anything Models: SAM2 and SAM3. We explain why the expertise in prompt-based segmentation of SAM2 does not transfer to the multimodal concept-driven paradigm of SAM3. SAM2 operates through spatial prompts points, boxes, and masks yielding purely geometric and temporal segmentation. In contrast, SAM3 introduces a unified vision-language architecture capable of open-vocabulary reasoning, semantic grounding, contrastive alignment, and exemplar-based concept understanding. We structure this analysis through five core components: (1) a Conceptual Break Between Prompt-Based and Concept-Based Segmentation, contrasting spatial prompt semantics of SAM2 with multimodal fusion and text-conditioned mask generation of SAM3; (2) Architectural Divergence, detailing pure vision-temporal design of SAM2 versus integration of vision-language encoders, geometry and exemplar encoders, fusion modules, DETR-style decoders, object queries, and ambiguity-handling via Mixture-of-Experts in SAM3; (3) Dataset and Annotation Differences, contrasting SA-V video masks with multimodal concept-annotated corpora of SAM3; (4) Training and Hyperparameter Distinctions, showing why SAM2 optimization knowledge does not apply to SAM3; and (5) Evaluation, Metrics, and Failure Modes, outlining the transition from geometric IoU metrics to semantic, open-vocabulary evaluation. Together, these analyses establish SAM3 as a new class of segmentation foundation model and chart future directions for the emerging concept-driven segmentation era.

cornell Cornell University
·
Dec 4, 2025 2

GeoSeg-OV: Bridging Geospatial Gaps with Structural Guidance for Open-Vocabulary Remote Sensing Segmentation

Open-vocabulary remote sensing segmentation has recently emerged as a promising paradigm that enables pixel-level recognition of arbitrary categories specified by natural language, including classes unseen during training. However, geospatial domain shifts caused by heterogeneous regions, spatial resolutions, and acquisition platforms weaken visual-text matching and limit cross-dataset generalization. Recent attempts have begun to incorporate auxiliary vision foundation models (VFMs), typically coupling their features with text embeddings as additional matching evidence. However, this strategy may introduce inconsistent matching signals while leaving the structure-sensitive representations of VFMs insufficiently exploited. We therefore propose GeoSeg-OV, which decouples auxiliary VFM features from visual-text matching and repurposes them as structural guidance for cost aggregation and decoding. GeoSeg-OV constructs an orientation-robust cost volume from multi-rotation CLIP features, while a frozen VFM extracts multi-scale structure-sensitive features in parallel. We propose Structure-Guided Aggregation (SGA), which integrates cost tokens and CLIP semantic guidance with VFM-derived pairwise structural biases for coherent spatial propagation, followed by text-conditioned class-wise reasoning. We further introduce Cost-Aware Decoding (CAD) to adaptively refine and fuse multi-scale semantic and structural guidance based on the current decoder context. On the global High-Resolution Land Cover (HRLC) benchmark spanning seven datasets across six continents, GeoSeg-OV outperforms the state-of-the-art by +2.5 and +2.7 average mIoU under two training settings. A large-scale zero-shot case study further demonstrates its generalization across geographic domains and category systems without target-domain annotations or retraining.

  • 7 authors
·
Aug 10

Mediastinal lymph nodes segmentation using 3D convolutional neural network ensembles and anatomical priors guiding

As lung cancer evolves, the presence of enlarged and potentially malignant lymph nodes must be assessed to properly estimate disease progression and select the best treatment strategy. Following the clinical guidelines, estimation of short-axis diameter and mediastinum station are paramount for correct diagnosis. A method for accurate and automatic segmentation is hence decisive for quantitatively describing lymph nodes. In this study, the use of 3D convolutional neural networks, either through slab-wise schemes or the leveraging of downsampled entire volumes, is investigated. Furthermore, the potential impact from simple ensemble strategies is considered. As lymph nodes have similar attenuation values to nearby anatomical structures, we suggest using the knowledge of other organs as prior information to guide the segmentation task. To assess the segmentation and instance detection performances, a 5-fold cross-validation strategy was followed over a dataset of 120 contrast-enhanced CT volumes. For the 1178 lymph nodes with a short-axis diameter geq10 mm, our best performing approach reached a patient-wise recall of 92%, a false positive per patient ratio of 5, and a segmentation overlap of 80.5%. The method performs similarly well across all stations. Fusing a slab-wise and a full volume approach within an ensemble scheme generated the best performances. The anatomical priors guiding strategy is promising, yet a larger set than four organs appears needed to generate an optimal benefit. A larger dataset is also mandatory, given the wide range of expressions a lymph node can exhibit (i.e., shape, location, and attenuation), and contrast uptake variations.

  • 5 authors
·
Feb 11, 2021